(NASDAQ: ADMP) today announced the submission of a New Drug Application (NDA) to the U. Food and Drug Administration (FDA) for its fast-dissolving sublingual tadalafil tablet. This product candidate is designed for the treatment of erectile dysfunction. Adamis submitted the NDA pursuant to Section 505(b)(2) of the Food, Drug & Cosmetic Act. Tadalafil (Cialis®) is a drug used for treating erectile dysfunction (ED), pulmonary hypertension and benign prostatic hyperplasia (BPH). Tadalafil is in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors which includes, among others, sildenafil (Viagra®) and vardenafil (Levitra®). All three drugs of these oral tablets are FDA approved and clinically indicated for the treatment of ED. Carlo, President and Chief Executive Officer of Adamis, stated, “The filing for the NDA for our tadalafil tablet represents an important milestone for our company. Tadalafil and sildenafil are also indicated for pulmonary hypertension, but among PDE5 drugs, only tadalafil is approved for the treatment of BPH. We are very pleased with the progress we have made with our tadalafil product candidate which we believe is well-positioned to compete in the large, multi-billion-dollar erectile dysfunction market. cialis reviews photos Simply leave the pills under your tongue and allow it to slowly dissolve. This is specially recommended if you are experiencing any stomach issue. Since the Tadalafil enters your body by being absorbed from the soft tissue in the mouth. You are over-passing the need for the stomach to dissolve the medication. We encourage our customer to first try the sublingual Tadalafil by buying a ED trial pack Penile erection during a sexual stimulation is caused by increased blood flow into the penile arteries. To ensure increased blood flow the muscles should be relaxed. A compound called as c GMP enables this relaxation. 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Our compounding pharmacists have developed innovative quick dissolving tablets (QDTs) that can be placed under the tongue. Both Tadalafil and Sildenafil are available in this unique dosage form, and many of Pavilion Compounding Pharmacy’s formulas cost as little as $2 per dose. Quick dissolve tablets do not need to be taken with a glass of water or food and may offer a more rapid onset of action. Our pharmacists have also developed quick dissolve tablets that combine Apomorphine with Tadalafil and Sildenafil. Apomorphine is an oral erectogenic agent taken sublingually (placed under the tongue). It exerts its effect in areas of the brain that are involved in the triggering of the erection cascade. Sublingual nitrates are generally placed under the tongue where they dissolve and are absorbed through the lining of the mouth. Some can also be used buccally, being placed under the lip or in the cheek. 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