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    Generic name: Furosemide (multiple manufacturers) Common U. S.) Class: Loop diuretic, sulfonamide (contains sulfa), antihypertensive Treatment Uses – For treatment of edema, including edema associated with heart failure or renal failure. S.) Popularity: Tenth most commonly prescribed drug between 2002-2006 (U. As an adjunct (for use with other medications) for treatment of acute volume overload states associated with heart failure. For treatment of hypertension; most often employed in combination with other antihypertensive agents, although probably effective if used alone. For treatment of ascites in patients with cirrhosis. Furosemide is also used to improve pulmonary function in infants with bronchopulmonary dysplasia (BPD). Nebulized furosemide may be beneficial for treatment of asthma in adults and children although the evidence supporting this use is not overwhelming. viagra how long Despite many advances in the treatment of hypertension, adequate blood pressure (BP) control in elderly patients continues to be a challenge. Optimal control of BP remains elusive because of issues relating to drug dosage and proper choice of therapeutic agents, including questions regarding the role of diuretics. We examined the effect of diuretic treatment on BP in 12 elderly hypertensive patients whose hypertension was poorly controlled on previous drug regimens. We also evaluated the relationship of systolic, diastolic, and mean arterial BP (SBP, DBP, MAP, respectively) to changes in plasma renin activity (PRA), serum aldosterone (SA), atrial natriuretic peptide (ANP), and serum chemistries both before and after adding furosemide to the prior antihypertensive agents. = .02), findings consistent with volume mediated/salt sensitive hypertension. In the remaining 33% of patients, BP also decreased significantly, but there was no increase in PRA (0.15 ± 0.05 to 0.10 ± 0 ng/m L/h) or SA (9.2 ± 2.2 to 7.0 ± 0.8 ng/d L) and no decrease in ANP (66 ± 5 to 75 ± 18 pg/m L) (Many of the elderly hypertensive patients in our study had decreased PRA levels and showed significant reductions in BP after furosemide administration. Despite the associated increases in PRA and SA and decreases in ANP in 67% of patients, diuretic use remains important in the control of hypertension in this population.

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    Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill. Get Started Comment: I have been taking this drug for water build up on my legs and feet doctor started me on 20 mg it worked fine for about a month then I started having a reaction to the med I had the jitters itchy feeling felt like things crawling on me hard time breathing and the swelling didn't go down. So the doctor had me to take 10 mg half pill I did that no prob with side effects but the swelling isn' ... Show Full Comment Comment: I have been taking this drug for water build up on my legs and feet doctor started me on 20 mg it worked fine for about a month then I started having a reaction to the med I had the jitters itchy feeling felt like things crawling on me hard time breathing and the swelling didn't go down. So the doctor had me to take 10 mg half pill I did that no prob with side effects but the swelling isn't going down. I had my husband buy me water pills from Walmart there called sundown naturals haven't tried them yet he just got them yesterday so I'm going to talk with the pharmacy to see if there safe to take with other medications. Absorption: 60–67% absorbed after oral administration (↓ in acute HF and in renal failure); also absorbed from IM sites. Metabolism and Excretion: Minimally metabolized by liver, some nonhepatic metabolism, some renal excretion as unchanged drug. TIME/ACTION PROFILE (diuretic effect)CNS: blurred vision, dizziness, headache, vertigo EENT: hearing loss, tinnitus CV: hypotension GI: anorexia, constipation, diarrhea, dry mouth, dyspepsia, ↑ liver enzymes, nausea, pancreatitis, vomiting GU: ↑ BUN, excessive urination, nephrocalcinosis Derm: Edema PO: (Adults) 20–80 mg/day as a single dose initially, may repeat in 6–8 hr; may ↑ dose by 20–40 mg q 6–8 hr until desired response. Distribution: Crosses placenta, enters breast milk. Maintenance doses may be given once or twice daily (doses up to 2.5 g/day have been used in patients with HF or renal disease). Hypertension– 40 twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%); adjust further dosing based on response; Hypercalcemia– 120 mg/day in 1–3 doses. PO: (Children 1 mo): 2 mg/kg as a single dose; may be ↑ by 1–2 mg/kg q 6–8 hr (maximum dose = 6 mg/kg). IM: IV: (Adults) 20–40 mg, may repeat in 1–2 hr and ↑ by 20 mg every 1–2 hr until response is obtained, maintenance dose may be given q 6–12 hr; Continuous infusion– Bolus 0.1 mg/kg followed by 0.1 mg/kg/hr, double q 2 hr to a maximum of 0.4 mg/kg/hr. IM: IV: Children 1–2 mg/kg/dose q 6–12 hr; Continuous infusion– 0.05 mg/kg/hr, titrate to clinical effect. Hypertension PO: (Adults) 40 twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%); adjust further dosing based on response. Tablets: 20 mg, 40 mg, 80 mg, 500 mg Cost: Generic: 20 mg $6.50/100, 40 mg $7.11/100, 80 mg $10.83/100Oral solution (10 mg/m L–orange flavor, 8 mg/m L–pineapple–peach flavor): 8 mg/m L, 10 mg/m LCost: Generic: 10 mg/m L $10.40/60 m LSolution for injection: 10 mg/m LLab Test Considerations: Monitor electrolytes, renal and hepatic function, serum glucose, and uric acid levels before and periodically throughout therapy. May cause ↓ serum sodium, calcium, and magnesium concentrations. May also cause ↑ BUN, serum glucose, creatinine, and uric acid levels.furosemide is a sample topic from the Davis's Drug Guide.

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