It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Medicine for lupus plaquenil Chloroquine retrovirus production Muscle risks might also increase in people who use a statin while taking cyclosporine drugs Gengraf, Neoral, which are used to treat rheumatoid arthritis. In general, the lowest statin dose possible should be prescribed to avoid muscle pain, a side effect in up to 10 percent of the people who take these medications. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Re Plaquenil and Statins Shari, *Maybe* the numbers that jumped out at your doctor were LDL at 114, that's above the 100 now recommended, and considerably above the 70 now seemingly being recommended for people with "risk factors"; and triglycerides at 219, that's much higher than the recommended 100. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and statins Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil Oral Interactions with Other Medication Plaquenil for chronic lymeHow long do you need to use plaquenilChloroquine and digoxinHow long does plaquenil take to work for lupusHydroxychloroquine prevent miscarriage Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Rx Side Effects New Plaquenil Guidelines and More.. Plaquenil and Statins - HealthBoards. Plaquenil Side Effects Common, Severe, Long Term -. Hi Kristy. I've tried various statins and I can take them for awhile and then they seem to build up in my body and I go into bad flares This is before I had been DX'd. So I am currently not taking any, but I'm concerned because my LDL is very high too. I am taking Plaquenil, but stopped the statin just before starting it. Hydroxychloroquine can be tough on its own to the liver. Statin drugs and many other drugs can also negatively impact the liver. I have been on Crestor 10mg for 15 years and plaquenil for 12 and all my liver tests are fine. All drugs have plusses and minuses. You have to make trade offs.based on your risk profile. Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. A new study tracked how they did.