Chloroquine diphosphate and phosphate

Discussion in 'Trust Pharmacy Canada' started by Antoniy, 17-Mar-2020.

  1. BigTank Moderator

    Chloroquine diphosphate and phosphate


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors TLRs. Chloroquine diphosphate is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. - Mechanism of Action & Protocol. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Most, if not all of the chloroquine available for aquarium use is in the form of chloroquine diphosphate as opposed to chloroquine hydrochloride or sulfate. This means that dosing an aquarium with this drug will also add some phosphate PO 4 to the water when the compound dissociates as it dissolves.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine diphosphate and phosphate

    Pharmacokinetics of chloroquine diphosphate in the dog., Chloroquine Indications, Side Effects, Warnings -

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  7. The chemical name of chloroquine phosphate in chemical abstracts is found under the heading Quinoline and designated as 7-Chloro- 4-4-diethylamino-1-methylbutylamino quinoline diphosphate. Chloroquine phosphate is a white, odorless, crystalline powder having a bitter taste it discolors gradually on exposure to light.

    • Chloroquine Phosphate - ScienceDirect.
    • Aquarium Fish Chloroquine A "New" Drug for Treating Fish..
    • CHLOROQUINE PHOSPHATE, USP.

    Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug. Sasaki et al 2010 Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370 PMID 20630104. If you know of a relevant reference for Chloroquine diphosphate, please let us know. Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis, rheumatoid arthritis, discoid and systemic lupus erythematosus. Application DNA intercalator. Also used to increase transfection efficiency. Chloroquine diphosphate salt has been used • in in vitro antiplasmodial assays

     
  8. Kirpich Well-Known Member

    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Chloroquine - FDA prescribing information, side effects and uses Chloroquine Sigma-Aldrich DailyMed - CHLOROQUINE PHOSPHATE- chloroquine phosphate.
     
  9. kosmodrom XenForo Moderator

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  10. ViGikant Guest

    Despite Plaquenil dosing recommendations, retinal toxicity. A cookie-cutter approach to dosing Plaquenil. “When you use real weight to calculate dose, the risk is exactly the same whether you weigh 90 pounds or 250 pounds. To me, that’s how drug.

    Hydroxychloroquine dosage recommendations often ignored.