Nigeria malaria chloroquine resistance

Discussion in 'Plaquenil' started by faxenoff, 12-Mar-2020.

  1. 64RIK New Member

    Nigeria malaria chloroquine resistance


    Resistance to currently available antimalarial drugs has been confirmed in only two of the four human malaria parasite species, first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted.

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    Resistance to anti- malarial drugs in patients is becoming a worrisome phenomenon in Nigeria. It has posed serious challenge of combating malaria in most parts of the world. Malaria is caused by four different protozoa Plasmodium Vivax which is more prevalent in low endemic areas, Plasmodium ovale, Plasmodium malariae and Plasmodium falciparum which is the most dangerous of the four. The prevalence of malaria is more dependent on the abundance of the female anopheles mosquito. The Nigeria Medical Association has debunked claims on social media that chloroquine phosphate is a cure for coronavirus, aka COVID-19, saying the anti-malaria drug is not a proven antidote.

    Although resistance to these drugs tends to be much less widespread geographically, in some areas of the world, the impact of multi-drug resistant malaria can be extensive. Has also developed resistance to nearly all of the other currently available antimalarial drugs, such as sulfadoxine/pyrimethamine, mefloquine, halofantrine, and quinine.

    Nigeria malaria chloroquine resistance

    Chloroquine resistance of Plasmodium falciparum is., Malaria in Nigeria; Causes, Effects and Possible Treatment.

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  7. Chloroquine-resistant P. vivax malaria was first identified in 1989 among Australians living in or traveling to Papua New Guinea. P. vivax resistance to chloroquine has also now been identified in Southeast Asia, Ethiopia, and Madagascar. Isolated reports have suggested chloroquine-resistance P. vivax in other countries and regions, but further evaluation is needed.

    • CDC - Malaria - Malaria Worldwide - How Can Malaria Cases..
    • Chloroquine not cure for coronavirus –NMA – Punch Newspapers.
    • CDC - Malaria - Travelers - Malaria Information and..

    Chloroquine was in use for more than 50 years before misuse and adulteration led to development of resistance by the malaria parasite and subsequent ban of the drug by the World Health Organisation. Facts about malaria in Nigeria. In Nigeria, malaria is endemic. Accounts for 60% of outpatient visits. Responsible for 30% of under-5 mortality. Resurgence of malaria is observed in recent times. Resurgence due to increasing resistance to chloroquine & sulfadoxine-pyrimethamine. The term “chloroquine resistance” can lead to misunderstandings when it is considered by some to refer to in vitro phenotypes, by others to refer to the ability of malaria parasites to survive chloroquine at therapeutic serum concentrations in vivo, and yet by others to refer to the outcome of a clinical episode after chloroquine therapy.

     
  8. Dumpty XenForo Moderator

    Please make sure that Javascript and cookies are enabled on your browser and that you are not blocking them from loading. PLAQUENIL Patient Assistance Program Hydroxychloroquine Price of 3 Brands / Trade Names Medindia Manufacturers of hydroxychloroquine and Suppliers. - Panjiva
     
  9. Summus Moderator

    Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs swollen or painful glands trouble with breathing, speaking, or swallowing

    Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  10. starsolaris Well-Known Member

    Evaluations from Patients who take Hydroxychloroquine. Patient evaluations for Hydroxychloroquine 1106 members have decided to share their profiles only with other members of PatientsLikeMe.

    Hydroxychloroquine Oral Route Description and Brand Names.