While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Hydroxychloroquine mechanism of action Plaquenil myositis How to pronounce chloroquine Areas with chloroquine or mefloquine resistance How to use Plaquenil Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. How does plaquenil help inflammation Inflammatory Osteoarthritis And Plaquenil, Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Plaquenil vs tacrolimus Many anti-inflammatory medications used for rheumatoid arthritis have been applied to inflammatory bowel disease IBD therapy. Hydroxychloroquine Plaquenil® has received little attention in Crohn’s disease CD. 1 This anti-malarial agent is an older disease-modifying anti-rheumatic drug and is used by rheumatologists for patients who try and fail or fear trying immunomodulator and biologic therapy. Hydroxychloroquine for Crohns Disease and Ulcerative Colitis.. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil hydroxychloroquine helps inflammation, will that.. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Also called Plaquenil, hydroxychloroquine is a disease-modifying drug that can help decrease both the swelling and pain of rheumatoid arthritis. According to Rheumatology.org, there is not a clear reason why hydroxychloroquine is so effective in treating autoimmune diseases. Dr. Krauser responded Yes. Fatigue is the result of the inflammation. If Plaquenil hydroxychloroquine works, it will also help the fatigue.