B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Bloodshot eyes plaquenil Plaquenil and blood pressure Chloroquine toxicity symptoms Hydroxychloroquine sulphate indications Hydroxychloroquine induced cutaneous pigmentation. cular hemosiderin on special staining. 3 Cutaneous hyperpigmentation has been suggested as a marker. 4 Millard TP, Kirk A, Ratnavel R. Cutaneous hyperpigmentation during therapy with hydroxychloroquine. Clin Exp Dermatol 2004;–3. 5 Dwyer CM, Cuddihy AM, Kerr RE, et al. Skin. Home April 2007 - Volume 13 - Issue 2 Cutaneous Hyperpigmentation During Therapy With Hydroxychlor. Log in to view full text. If you're not a subscriber, you can Reactions 1565, p109 - Cutaneous hyperpigmentation 4 case reports Four men developed cutaneous hyperpigmentation during treatment with doxycycline and hydroxychloroquine routes not stated. A 75-year-old man with chronic Q fever received doxycycline 200 mg/day; he had been receiving hydroxychloroquine 400 mg/day for 5 years for rheumatoid arthritis. After 4 months, his. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Cutaneous hyperpigmentation during therapy with hydroxychloroquine Plaquenil Side Effects Common, Severe, Long Term -, Cutaneous Hyperpigmentation During Therapy With Hydroxychlor. Chloroquine slideshareHydroxychloroquine for sjogren's syndromePlaquenil price ireland What is drug-induced skin pigmentation. Drug-induced skin pigmentation accounts for 10–20% of all cases of acquired hyperpigmentation. Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs NSAIDs, phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals. Drug-induced hyperpigmentation DermNet NZ. Doxycycline/hydroxychloroquine, Reactions Weekly 10.1007.. Hydroxychloroquine-Induced Pigmentation in Patients With.. Cutaneous Hyperpigmentation During Therapy with Hydroxychloroquine. By Zennure Takcı, Zennure Özdemir Yılmaz and Gülçin Güler Şimşek. Cite. BibTex; Full citation; Topics Dermatology. Home April 2007 - Volume 13 - Issue 2 Cutaneous Hyperpigmentation During Therapy With Hydroxychlor. Log in to view full text. If you're not a subscriber, you can You can read the full text of this article if you. Cutaneous Hyperpigmentation During Therapy With Hydroxychloroquine. Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis.