Chloroquine phosphate, which has been used for more than 70 years and is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system. Chloroquine was discovered in 1934 by Hans Andersag but was initially ignored for a decade because it was considered too toxic for human use. Plaquenil months Precaution of chloroquine Lupus hydroxychloroquine sulfate Plaquenil addictive Oct 12, 2016 Following a single dose, chloroquine may be detected in plasma for more than four weeks. Mean bioavailability from tablets of chloroquine phosphate is 89%. Chloroquine is widely distributed in body tissues such as the eyes, kidneys, liver, and lungs where retention is prolonged. Plaquenil hydroxychloroquine and Aralen chloroquine phosphate are antimalarial medications used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. The dose of chloroquine is often expressed or calculated as the base each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg chloroquine base. -The pediatric dose should never exceed the adult dose. Aside from preventing and treating malaria, chloroquine is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. During World War II, United States government-sponsored clinical trials for antimalarial drug development showed unequivocally that chloroquine has a significant therapeutic value as an antimalarial drug. Chloroquine phosphate lupus Aralen Chloroquine MyLupusTeam, Plaquenil vs. Aralen Prescription Treatment for Malaria. Hydroxychloroquine vidalChloroquine contraindications The sulfate and phosphate salts of chloroquine have both been commercialised as antimalarial drugs. Hydroxychloroquine has also been used as an antimalarial, but in addition is now broadly used in autoimmune diseases such as lupus and rheumatoid arthritis. Of chloroquine and COVID-19 - ScienceDirect. Chloroquine Dosage Guide with Precautions -. Anti-malaria drug being tested for efficacy against COVID-19. Chloroquine is a very cheap and safe drug that has been used for decades to treat is efficacious as an anti-inflammatory agent for the treatment of rheumatoid arthritis and lupus erythematosus. Consequently, Gao et al,2020 recommends Chloroquine phosphate to treat COVID-19 associated pneumonia in larger populations. Chloroquine can be used to kill malaria parasites living in red blood cells but the medication may not necessarily be efficient at killing these parasites in other body tissues. Doctors often prescribe this medication as part of certain treatment plans for lupus and other immune system diseases. Amebiasis treatment oral To treat amebiasis in adults, one oral dose of chloroquine is usually taken for two days. Then, half the dose is given every day for two to three weeks. Ask your doctor.