Please review the following URL and make sure that it is spelled correctly. Up to 60 percent of adults report that they have had nocturnal leg cramps. Multifocal erg plaquenil toxicity Define hydroxychloroquine Lupus myositis often affects the muscles of your neck, pelvis, thighs, shoulders and upper arms; difficulty in climbing stairs and getting up from a chair are early symptoms. Later symptoms may include difficulty lifting objects onto a shelf, lifting your arm to comb or brush your hair, getting out of the bath. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. Nocturnal leg cramps are associated with vascular disease. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. Plaquenil and muscle spasms Plaquenil and muscle aches and pains?, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil maculopathy symptoms Muscle Spasm Definition Muscle spasms are typically painful involuntary muscle contracures which can occur in any part of the body, such as the neck, back and legs. There are various causes of muscle spasms such as recent injury or trauma and dehydration. Typically, patients can modify activity, rest, stretch. Does lupus cause muscle spasms - Answers on HealthTap. Nocturnal Leg Cramps - American Family Physician. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Jul 18, 2008 I have already decided to stop taking it until I can speak with my rheumy. I have another medical condition that could cause this severe back pain. I'm thinking this is likely a coincidence that I developed this problem right after starting the Plaquenil. Also, does anyone know what typr of muscle damage Plaquenil can cause? Sep 17, 2016 Among her worst symptoms of this horrible flare are very severe muscle spasms and intense neuropathy. When she tries to relax in the evening and into the night, these muscle spasms kick in. They are so severe that we've made multiple trips to the ER for IV meds. Jun 25, 2013 Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication.