PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Plaquenil used for alopecia Plaquenil and vision Nov 02, 2018 At the 2018 ACR/ARHP Annual Meeting, I had the opportunity to co-moderate this year's Great Debate, which was titled "Guidelines for SLE HCQ Dose Should Be No More Than 5 mg/kg In All Patients." Dr. Nathalie Costedoat-Chalumeau of the Cochin Hospital in Paris began the symposium by briefly discussing the risks and benefits of hydroxychloroquine HCQ, and her own work on the use of hydroxychloroquine blood levels. From a practical perspective, this means the daily dose should be reduced below 400 mg per day for those weighing less than 61 kg 134 lbs. Hydroxychloroquine Blood Levels and Adherence. As with most chronic diseases, medication adherence in SLE is a challenge, which associates with poor clinical outcomes. Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine dose sle Hydroxychloroquine in systemic lupus erythematosus SLE., RheumNow Hydroxychloroquine Blood Levels in SLE MedPage Today What happens if you quit taking plaquenilPlaquenil drug usesHydroxychloroquine nursing interventionsSierra leone chloroquineCvs caremark does not cover plaquenil CHICAGO — Hydroxychloroquine has many indications, including systemic lupus erythematosus. In this setting, it has been shown to reduce flares, prevent organ damage, reduce cardiovascular risks. Experts debate hydroxychloroquine dosing guidelines in lupus. Hydroxychloroquine Plaquenil. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. The safety and efficacy of the chronic use of hydroxychloroquine for systemic lupus erythematosus and juvenile idiopathic arthritis in children and infants have not been established. Children are especially sensitive to the 4-aminoquinoline compounds. Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. Hydroxychloroquine therapy has not been associated with liver function abnormalities and is an extremely rare cause of clinically apparent acute liver injury.