Malaria prophylaxis chloroquine resistant areas

Discussion in 'Hydroxychloroquine' started by Gotheus, 29-Feb-2020.

  1. Kirik Guest

    Malaria prophylaxis chloroquine resistant areas


    Each year up to 30 000 travelers are estimated to contract malaria and late or wrong malaria diagnosis in their home country may make things worse for them. Fever occurring in a traveler within three months of leaving a malaria-endemic area is considered a medical emergency and should be investigated urgently.

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    Chloroquine and hydroxychloroquine Chloroquine targets blood schizonts. There is considerable resistance to these medications, and they should only merit consideration for travelers to areas with chloroquine-sensitive P. falciparum the Caribbean, Central America west of the Panama Canal, and some parts of the Middle East. Travelers start the. Chloroquine shouldn’t be used for treatment of P. falciparum infections from areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Despite the growing stories due to resistance of parasite to chloroquine in some parts of the world. this drug remains one of the most widespread to malaria. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Gabon All Chloroquine P. falciparum 90%, P. malariae, P. ovale, P. vivax 10% combined

    And as malaria can be severe in the non-immune, all visitors from non-malarious area to a malarious area should be protected. As there is no vaccine available for protection against malaria despite decades of research, there is a need for an alternative method that offers a fairly reliable protection against malaria.

    Malaria prophylaxis chloroquine resistant areas

    Long-Term Travelers & Expatriates - Chapter 9 - 2020., Where is chloroquine resistant malaria ZCARR

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  3. Searches for new drugs against chloroquine-resistant malaria, especially as they relate to analogues of chloroquine and chemosensitizing agents against the different forms of P. falciparum and P. vivax, should benefit greatly from research work in this area

    • Chloroquine-Resistant Malaria The Journal of Infectious..
    • CDC - Malaria - Travelers - Malaria Information and..
    • Malaria Travel & Health Guide, 2019 Online Book.

    Chloroquine is used for the prophylaxis of malaria in areas of the world where the risk of chloroquine-resistant falciparum malaria is still low. It is also used with proguanil when chloroquine-resistant falciparum malaria is present. Now, chloroquine resistant forms of P. vivax are found in multiple locations in south-east Asia, such as Myanmar and India, as well as from Guyana in South America. Nowadays, other drugs, and notably ones containing artemisinin-based compounds, are preferentially used to treat uncomplicated malaria and especially in areas where chloroquine resistance is known to occur. Chloroquine is used for the prophylaxis of malaria in areas of the world where the risk of chloroquine-resistant falciparum malaria is still low. It is also used with proguanil when chloroquine-resistant falciparum malaria is present. However, this combination may not be ideal.

     
  4. x-maika XenForo Moderator

    Hydroxychloroquine is a disease-modifying anti-rheumatic drug (DMARD). Managing reactive arthritis Rheumatology Oxford Academic Taking Plaquenil for Rheumatoid Arthritis Diagnosis and Treatment of Lyme Arthritis
     
  5. OLGA K. XenForo Moderator

    What Is Hydroxychloroquine and How Does It Help Arthritis. Also called Plaquenil, hydroxychloroquine is a disease-modifying drug that can help decrease both the swelling and pain of rheumatoid arthritis. According to, there is not a clear reason why hydroxychloroquine is so effective in treating autoimmune diseases.

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.