It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Does plaquenil interact with gerd Hydroxychloroquine and nerve damage Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. User Reviews for Hydroxychloroquine to treat Undifferentiated Connective Tissue Disease. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare. Mixed connective-tissue disease MCTD was first recognized by Sharp and colleagues 1972 in a group of patients with overlapping clinical features of systemic lupus erythematosus SLE, scleroderma, and myositis, with the presence of a distinctive antibody against what now is known to be U1-ribonucleoprotein RNP. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Mctd and plaquenil How effective is Plaquenil for Mixed connective tissue., User Reviews for Hydroxychloroquine to treat. - Plaquenil and general anesthesiaFda hydroxychloroquine Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of anti-malarials as a sort of “lupus life insurance.” Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Mixed Connective-Tissue Disease Medication Nonsteroidal anti.. Plaquenil and MCTD - Reviews - Treato. Welcome! You are definitely in the right place with MCTD. We're kind of the autoimmune-what-the-heck-is-going-on-with-me support group. Plaq was a big help to me on fatigue, rashes, and stopping that peskly low grade fever. I hope it will help you, too. Mixed connective tissue disease MTCD is an uncommon systemic inflammatory rheumatic disease. MCTD is a specific subset of the broader category of rheumatic “overlap syndromes”, a term used to describe when a patient has features of more than one classic inflammatory rheumatic disease. MCTD Support Group. Mixed connective tissue disease MCTD or Sharp's syndrome is a human autoimmune disease in which the immune system attacks the body. MCTD combines features of polymyositis, systemic lupus erythematosus, and systemic scleroderma and is thus considered an overlap syndrome.