Differential diagnosis of concomitant SLE and IBD is difficult and should always exclude infectious conditions, lupus-like reactions, visceral vasculitis and drug-induced lupus. The underlying mechanism by which 5-ASA/sulphasalazine induces SLE or lupus-like syndromes is not clear and high awareness for possible predictive factors is demanded for early prevention. Chloroquine-resistant malaria may be treated with __________ Oct images of plaquenil toxicity Sulphasalazine-induced lupus syndrome in ulcerative colitis has been reported in seven42, 44, 45, 46 patients including one child 46 among them. In one of these patients 42 with salazosulfapyridine-induced lupus syndrome the connection with medication was ascertained by re-exposition. Arthralgia is more common among patients with IBD, occurring in 40-50% of patients, which is a rate similar to that of the general population; arthritis occurs in approximately 15—20% of Crohn's disease CD patients and approximately 10% of ulcerative colitis UC patients at some stage during their disease course. Sulphasalazine-induced lupus syndrome in ulcerative colitis has been reported in seven 42, 44 – 46 patients including one child 46 among them. In one of these patients 42 with salazosulfapyridine-induced lupus syndrome the connection with medication was ascertained by re-exposition. Treatment of patients co-diagnosed with SLE and IBD may include corticosteroids, immunosupressants and hydroxychloroquine. In most cases the symptoms from drug-induced lupus have been reversible after the discontinuation of the drug and response to steroids is favorable. Plaquenil ulcerative colitis Irritable Bowel/Ulcerative Colitis ? Lupus Related, Management of Arthritis in Patients with Inflammatory Bowel. Hydroxychloroquine sulfate plaquenil side effectsChloroquine phosphate for malariaPlaquenil and scleroderma Sulfasalazine is used to reduce inflammation and pain in rheumatoid arthritis RA, juvenile rheumatoid arthritis JRA, and ulcerative colitis UC. In RA and JRA, the medication is used to treat people who haven’t responded to other therapies. It’s used to decrease pain and swelling in the joints. Sulfasalazine Side Effects, Dosage, Uses, and More. Inflammatory bowel disease and lupus A systematic review.. Inflammatory Bowel Disease Arthritis Foundation. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Ulcerative colitis UC symptoms range from mild to severe. Symptoms may vary over time and from person to person, depending on what part of the large intestine is inflamed and the severity of the inflammation Immune response to tissue injury that causes redness, swelling, and pain. For Ulcerative Colitis "I had a flare of ulcerative colitis due to life stress. Was bleeding again. Xeljanz @ a dose of 10mg x day, it took 3 days to start getting no blood in stool. Quite amazing. I do have an ear infection though that I got from my small daughter so I'm taking precaution.