HCQ remains the major immunomodulatory agent used to treat systemic lupus erythematosus (SLE), but newer screening techniques have raised concern regarding potential eye toxicity. The 2016 American Academy of Ophthalmology (AAO) Recommendations for Screening for Hydroxychloroquine and Chloroquine Retinopathy recommended a maximum daily HCQ use of 5.0 mg/kg real weight. Plaquenil ga Plaquenil to treat alopecia Oct image plaquenil toxicity Mylan hydroxychloroquine Adapted from the American College of Rheumatology HYDROXYCHLOROQUINE Generic Name Brand Names Plaquenil WHAT IS IT? Hydroxychloroquine is a DMARD Disease Modifying Anti-Rheumatic Drug used to treat discoid or systemic lupus erythematosus lupus and rheumatoid arthritis RA in patients whose symptoms have not improved with other treatments. Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. American College of Rheumatology ACR Summary Hydroxychloroquine Plaquenil®, especially at the higher standard dose of 400 mg per day, independently decreases the risk of cardiovascular. Dr Rosenbaum is Professor of Ophthalmology, Medicine, and Cell Biology and Chair of the Division of Rheumatology at the Oregon Health & Science University. The AAO also recommends a baseline fundus examination and annual screening after 5 years for patients without major risk factors. Rosenbaum, MD, took the “pro” side of the debate, arguing that the AAO Guidelines are appropriate. Hydroxychloroquine plaquenil american college of rheumatology Hydroxychloroquine dosage recommendations often ignored., AMERICAN COLLEGE OF RHEUMATOLOGY Plaquenil immunosuppressant side effectsAlternativesto taking plaquenil Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Recommendations on Screening for Chloroquine and.. Hydroxychloroquine reduces cardiovascular morbidity risk.. What are the side effects of using hydroxychloroquine.. Patients met SLE criteria from either the 1997 American College of Rheumatology and/or 2012 Systemic Lupus Collaborating Clinics classification criteria and were monitored for ASA use, cumulative HCQ c-HCQ, and thrombotic events every 3 to 6 months. The position statement on hydroxychloroquine retinopathy provided by the American College of Rheumatology ACR—and reviewed by the American Academy of Ophthalmology AAO in Ophthalmology 2002; 177–82— recommends that all individuals starting HCQ have a complete baseline ophthalmologic exam within the first year of treatment, to. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day.