But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. A number of reports have linked methotrexate with lymphoma and similar cancers of the lymph glands, says senior researcher Shannon C. Kenney, MD, a microbiologist and infectious disease specialist with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill. Plaquenil 3 times a week Methotrexate and plaquenil for psoriatic arthritis Hydroxychloroquine and infertility Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side effects. Taking cyclosporine with hydroxychloroquine can increase the amount of cyclosporine in. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Reduces inflammation and cell replication. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Some studies have indicated that the drug's immune-weakening effect places people at risk for viral-associated lymphomas. Also, studies have shown that when rheumatoid arthritis patients quit taking methotrexate, their lymphoma went into regression, another sign that the drug directly contributes to the cancer, she tells Web MD. Hydroxychloroquine increse methotrexate Methotrexate and plaquenil - @Kristinsaba1988 - Scleroderma., Hydroxychloroquine Side Effects, Dosage, Uses, and More Does plaquenil interact with migreliefPlaquenil arthritis australiaChloroquine boots price Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Plaquenil hydroxychloroquine sulfate dose, indications.. Compare Plaquenil vs Methotrexate -. Methotrexate vs Plaquenil Comparison -. Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Use hydroxychloroquine as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take hydroxychloroquine with food or milk. Swallow whole. Do not chew, break, or crush. Keep taking hydroxychloroquine as you have been told by your doctor or other health care provider, even if you feel well.