Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Dosage of chloroquine syrup for children Dmards for rheumatoid arthritis instead of plaquenil Hydroxychloroquine oral tablet doesn’t cause drowsiness, but it can cause other side effects. More common side effects. The more common side effects that can occur with hydroxychloroquine include Side effects of hydroxychloroquine are uncommon, but may include indigestion, diarrhoea, headaches and rashes. Hydroxychloroquine may also cause more serious side effects in a small number of people. For example, in rare cases, this medicine can cause eye damage. Hydroxychloroquine, originally used as an antimalarial agent, has beneficial effects on mucocutaneous symptoms in systemic lupus erythematosus. It is also used for the skin rash of discoid lupus erythematosus. A number of rare but serious adverse reactions can occur with its use and are usually associated with long-term therapy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can hydroxychloroquine cause a lupus type rash Hydroxychloroquine - Wikipedia, Lupus symptoms & treatments - Illnesses & conditions NHS inform Plaquenil alcohol liverHydroxychloroquine gh 200 mgHydroxychloroquine sun pharmaceuticalsGeneric plaquenil prices I believe that the difference between generic and brand name Plaquenil is possibly sulfa. I can take brand name Plaquenil the first few weeks cause stomach upset, but if I take the generic - I get a rash, sore throat and it's hard to swallow. Exactly what I get when I took a sulfa drug when I was a child. The generic probably contains sulfa. Allergic reaction to Plaquenil Lupus Forums at The Lupus.. Risks of Hydroxychloroquine. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. As noted, the most common antimalarial used is Plaquenil hydroxychloroquine, which is dosed by weight and used for persistent rashes. Evidence suggests that early use may delay systemic onset of lupus.