These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil and brain dizziness Calcium chloroquine tcr review Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 57,733 people who have side effects while taking the drug from Food and Drug Administration FDA. The information that eHealthMe analyzes includes If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Side effects of long term use of plaquenil What are the side effects of Plaquenil?, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Does plaquenil work for osteoarthritisDo you need a baseline eye exam before taking hydroxychloroquine For long-term use, the dose of hydroxychloroquine is usually reduced to 200 mg to 400 mg daily. Malaria The recommended preventative adult dose is 400 mg on exactly the same day of each week, beginning 2 weeks before exposure and continued for 8 weeks after leaving the high-risk area. Plaquenil - Uses, Side Effects, Interactions -. Common Plaquenil side effects a study from FDA data.. Continuation of long term treatment with.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. You may report side effects to FDA at 1-800-FDA-1088. Back to Top.