While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Plaquenil and pain relief Plaquenil ga What can Hydroxychloroquine Plaquenil do to my eyes? Hydroxychloroquine Plaquenil was originally used to treat malaria and is now used mostly to treat rheumatological and dermatological diseases. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms. She said that she previously didn't think that Plaquenil helped with dry mouth and eyes, but lately has been hearing the opposite and that I "provided very convincing evidence" that it does help. She said that she now believes Plaquenil may help improve the quality of saliva but there's no known way to measure the quality of saliva. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil belongs in a class of medications known as disease-modifying antirheumatic drugs DMARDs. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. Does plaquenil help dry eyes Common and Rare Side Effects for Plaquenil Oral, Plaquenil and dry mouth and eyes - Sjogren's World Plaquenil retinal toxicity doseIs plaquenil a dmardHydroxychloroquine 200 mg for rheumatoid arthritis However rheumy says plaquenil does not target the specific symptoms of dry eyes and dry mouth. She is right. I treat my dry eyes with restasis drops and the dry mouth comes and goes. Study Raises Questions about Sjogren's and Plaquenil. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil Side Effects on Your Eyes and Vision. Sjögren’s syndrome, which causes dry eyes and dry mouth. Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. For most people with Sjogren’s syndrome, treating dry eye and dry mouth are enough to enhance the quality of their lives. But in those who develop joint pain, fatigue, nerve dysfunction, or fibromyalgia, symptoms can be treated with mild medications.