I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine systemic lupus erythematosus Hydroxychloroquine generic substitute Hydroxychloroquine fever usmle New plaquenil dosing guidelines I had to stop Plaquenil after a few days. I couldn't walk, was dizzy, my speech was slurred, blurry vision, etc. but, I'm the one who usually gets side effects. I know people who Plaquenil has worked wonders. The side effects cleared up within a week. I also have Sjorgens, and my eyes were dryer on Plaquenil, but the blurry vision was the worst. Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Note that chloroquine is not used frequently in the United States and has been replaced by the use of hydroxychloroquine because the latter has fewer side effects. The Plaquenil Problem “Plaquenil toxicity is very distinctive,” said Michael F. Marmor, MD, professor of ophthalmology at Stanford University. Dr. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Any side effects from stopping plaquenil Stopping Plaquenil - General Discussion - Life With Lupus, Plaquenil Withdrawal – Life As An Anomaly Plaquenil visual field defectsHydroxychloroquine weightHydroxychloroquine hydroxyzine interaxtionHydroxychloroquine in lupus pregnancy.Plaquenil and trintellix interactions Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; skin rash; If you experience any of the following symptoms, call your doctor immediately Hydroxychloroquine MedlinePlus Drug Information. Rx Side Effects New Plaquenil Guidelines and More - American.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Jan 30, 2018 Hi, I've been taking Plaquenil for many years now and have never experienced any side effects or long term effects. But headache is listed as one of the "mild adverse effects". I would suggest that you try to split the dose as suggested. I've always taken 1 in the AM & 1 at night. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly.