It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hypoglycemia plaquenil Interaction between hydroxychloroquine and methotrexate If hydroxychloroquine was ineffective would it be effective with methotrexate Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. On days when I have to go out to work early it's a nightmare fitting them all in. I asked the rheumy whether I could take both doses of Plaquenil together but he said it was better to space them out. I find they make my reflux worse if I take a dose too close to bedtime and if my reflux is bad I need to take a second dose of Lanzoprazole before. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Days plaquenil to work Protecting your eyesight when taking Plaquenil Lupus., RA and Hydroxychloroquine How Effective is it for. Plaquenil and moodAralen dosisChloroquine selleckChloroquine prevention dosePlaquenil and parkinson's Your doctor may adjust your dose if needed. However, dose is usually not more than 600 mg or 6.5 mg per kilogram kg of body weight per day, whichever is lower. Children—Use and dose must be determined by your doctor. For treatment of lupus Adults—200 to 400 milligrams mg taken as a single dose or in two divided doses once a day. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. When best time of day to take plaquenil? - LUPUS UK. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Mar 24, 2011 I am glad I switched to the cymbalta, perhaps the combination of it and 400 mg of plaquenil will work for me. It seemed to help the swelling in my hands too. I had an uncle with RA whose been dead for years now but it was before all the better drugs came out and he was so crippled up.