Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine for ra Hydroxychloroquine 200 mg does it make u gain weight Falciparum malaria remains a major cause of disease and death among children and pregnant women in sub-Saharan Africa. During the second half of the 20th century, chloroquine was the antimalarial. With doxycycline, tetracycline, or clindamycin, recommended as a preferred regimen for treatment of uncomplicated malaria due to chloroquine-resistant or unknown resistance P falciparum or species not identified; in pregnant women, this drug should be used with clindamycin. Development of resistance to chloroquine CQ and other drug treatment in Plasmodium falciparum malaria has led the World Health Organization WHO to change its recommendations to adopt artemisinin combination therapy ACT as the first-line drug for the treatment of P. falciparum malaria cases in most endemic countries. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Treatment of chloroquine resistant falciparum malaria Chloroquine-resistant falciparum malaria Responsiveness., Quinine Dosage Guide with Precautions - Hydroxychloroquine couppnChloroquine and proguanil priceUses for hydroxychloroquineDoes plaquenil make you sun sensitive In addition, any of the regimens listed for the treatment of chloroquine-resistant malaria may be used for the treatment of chloroquine-sensitive. P. falciparum. malaria. Prompt initiation of an effective regimen is vitally important, so using any one of the effective regimens that is readily available would be the preferred strategy. Treatment of Malaria Guidelines for Clinicians United.. Efficacy of Chloroquine for the Treatment of Uncomplicated.. CDC - Malaria - Diagnosis & Treatment United States.. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Gabon All Chloroquine P. falciparum 90%, P. malariae, P. ovale, P. vivax 10% combined Plasmodium falciparum malaria in Haiti is considered chloroquine susceptible, although resistance transporter alleles associated with chloroquine resistance were recently detected. Among 49 patients with falciparum malaria, we found neither parasites carrying haplotypes associated with chloroquine resistance nor instances of chloroquine treatment failure. In Zambia, chloroquine was used as first-line treatment for uncomplicated malaria until treatment failures led the Ministry of Health to replace it with artemether-lumefantrine in 2003. Specimens from a recent study were analysed to evaluate prevalence of chloroquine-resistant malaria in Nchelenge district a decade after chloroquine use was discontinued.