Plaquenil is usually used for long term disease control, rather than in the short term to control active bursts of inflammation. Plaquenil has important but uncommon side effects that may affect your eye. The most important affect of Plaquenil on your eye is to damage the retina at the back of your eye. Areas with chloroquine or mefloquine resistance Does chloroquine affect birth control Chloroquine phosphate tablets used for Plaquenil make me itch Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble. This sort of retinal damage may result in patchy loss of central vision or patchy loss of vision just close to the centre of your vision. Fortunately, this is very uncommon and generally only occurs in patients on high doses or patients with bad kidney function. Hydroxychloroquine and eyes RCOphth guideline Hydroxychloroquine and Chloroquine., Hydroxychloroquine Plaquenil What type muscle weakness with plaquenil Feb 19, 2020 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” Sir, We agreed with the conclusions of Latasiewicz et al 1 ‘Hydroxychloroquine retinopathy an emerging problem’, which cited cases of hydroxychloroquine HCQ-induced retinal damage. Three patients had received 400 mg HCQ daily for over 15 years equaling 4.93 mg/kg/day in two and 5.6 mg/kg/day in one and all developed maculopathies of varying severity. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to.