In particular, when utilized in psoriatic arthropathy, they have been reported to induce pustular eruption (2), erythroderma (3) and pustular psoriasis (4). We report here a patient with psoriasis and subacute cutaneous lupus erythematosus (SCLE) who was treated successfully with hydroxychloroquine. How long for plaquenil drug eruption to go away Chloroquine avloclor Plaquenil with ldn Hydroxychloroquine for psoriasis Most patients who use methotrexate to treat their inflammatory arthritis take between 10 and 25 milligrams mg per week. By contrast, the doses used to treat leukemia and certain other types of cancer may be hundreds of times larger. That’s not to suggest that taking methotrexate is risk-free. Methotrexate has been used for decades to help with pain and swelling, and it can slow PsA progression over time. Folic Posted by on Monday, November 14, 2016 At the same time the psoriatic lesions became more inflamed and larger. Because of a positive rheumatoid test, she was diagnosed as having rheumatoid arthritis RA and given 7.5 mg/day prednisone and 10 mg/week methotrexate. The arthralgia improved, but the psoriatic lesions did not. CASE REPORT A 66-year-old woman had vitiligo for 40 years and psoriasis for 30 years with lesions localized on the extensory face of her elbows. A critical review of the literature casts some doubts on the contraindication of antimalarials in psoriasis. Methotrexate and plaquenil for psoriatic arthritis Methotrexate vs Plaquenil Comparison -, Methotrexate? Psoriatic- Plaquenil for angioedemaPlaquenil taken with uroxatralPlaquenil myositisPlaquenil and estrogen Benefits Hydroxychloroquine is a relatively safe medicine that is used to treat mild rheumatoid arthritis. It is also used for complications of lupus. It is also used for complications of lupus. Risks Hydroxychloroquine has few side effects, but nausea and diarrhea may occur when you first start taking the drug. DMARDs Arthritis Foundation. Hydroxychloroquine in Psoriasis Is it Really Harmful.. Coronavirus and Arthritis What You Need to Know Arthritis.. Methotrexate MTX is now the most popular drug worldwide for the treatment of rheumatoid arthritis. Low-dose, weekly MTX 10 to 25 mg/wk used as either monotherapy or in combination with other drugs has a superior efficacy profile as defined in placebo-controlled trials and comparable efficacy to other drugs including anti-TNF therapy. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Not only is methotrexate beneficial for people with psoriasis, it’s also helpful for those diagnosed with psoriatic arthritis. This type of arthritis is different than RA in that psoriasis generally precedes issues in the joints. In some cases though, no psoriasis-type symptoms exist at all.