Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What happens if you stop plaquenil Chloroquine 250 mg tab Glioblastoma chloroquine Screening requires the use of tests, such as 10–2 visual fields and SD-OCT and other modern techniques, such as autofluorescence imaging and multifocal electroretinography, to demonstrate early retinal damage.” 1 Melles & Marmor. The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy. The other major concern with maculopathy is that it may cause test abnormalities that interfere with the interpretation of screening procedures visual fields, SD OCT, fundus autofluorescence FAF, multifocal electroretinogram mfERG. Thus, significant central photoreceptor loss would be a contraindication. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Early plaquenil visual field New Plaquenil Guidelines, Recommendations on Screening for Chloroquine and. Chloroquine phosphate eye dropsMalaria medicine hydroxychloroquinePlaquenil arthritis medicationBiotin and plaquenil The latter provides the equivalent of an objective visual field and is especially useful to verify early or unreliable field changes. Fields may be sufficient for initial screening where SD-OCT is not available, and SD-OCT change is unlikely if a reliable field shows no losses at all. Disparity between Visual Fields and Optical Coherence.. Multimodal Imaging in Plaquenil Toxicity. Plaquenil - FDA prescribing information, side effects and uses. Early retinopathy has been defined as an acquired, persistent paracentral scotoma visualized on automated visual field testing without any observable fundus changes. 1 Reports have shown that the visual loss from HCQ toxicity is less likely to be reversible once fundus changes are present. 1,2,3 Although newer testing modalities, such as spectral domain-optical coherence tomography, fundus autofluorescenece, and multifocal electroretinogram, are now recommended as part of screening when. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. In early cases of toxicity, visual fields will typically reveal a paracentral scotoma. If a 24-2 or 30-2 field is performed, be way of overlooking the 2-degree field of sparing seen on 10-2 fields; in these tests, a small central defect may be seen instead.