It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Malaria chemoprophylaxis chloroquine phosphate tablet 500 mg in the news Brain fog plaquenil Chloroquine topical In patients with rheumatoid arthritis, combination therapy with methotrexate, sulfasalazine, and hydroxychloroquine is more effective than either methotrexate alone or a combination of. Methotrexate for Your RA. Methotrexate is one of the most effective medications to treat rheumatoid arthritis RA. It's the first drug most doctors prescribe after you’re diagnosed. It will. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Which is more effective methotrexate or plaquenil Methotrexate and plaquenil -, How Does Methotrexate Treat Rheumatoid Arthritis? - WebMD Chloroquine intercalating dna Methotrexate was more effective than hydroxychloroquine in treating refractory lichen planopilaris. Further multi-center studies with larger sample sizes and longer follow-ups are warranted. Financial support and sponsorship This study was supported by Isfahan University of Medical Sciences. Conflicts of interest There are no conflicts of interest. Clinical efficacy and safety of methotrexate versus.. RA and Hydroxychloroquine How Effective is it for.. Methotrexate for RA Side Effects, Effectiveness. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications.