Suddenly I'm experiencing eye problems (blilnd spots). I have stopped taking plaquenil, but now I'm being told by doctors that the damage is not necessarily reversible especially if you have taken it for a long time. Hydroxychloroquine in type 2 diabetes Plaquenil for inflammatory osteoarthritis Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Sign/Symptoms Retinal Damage. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. In doing those tests once a year we should be able to prevent progression of retinal damage.”. Those are early signs that you might be developing Plaquenil retinopathy,” says Katz. There are guidelines on the amount of Plaquenil a person should be able to take safely in a lifetime, and Katz encourages those taking the medication to. My mother was diagnosed with Plaquenil Toxicity in 2007 she first noticed changes in 2006, although being followed by her eye doctor they failed to notice this as Plaquenil TX until it was to late. I'm hoping to find people who have recovered from the eye damage. Signs of retinal damage from plaquenil The Risk of Retinal Toxicity with Plaquenil, Long-Term Side Effects of Plaquenil for Rheumatoid. Plaquenil cause fatigue Critical Warning Signs of Retinal Damage Have you been dealing with vision problems recently that are worse than normal? If you see any of these symptoms, chances are you have retinal damage and should seek us out for assistance. Critical Warning Signs of Retinal Damage Magruder Eye Institute. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Plaquenil-induced toxic maculopathy was first described in 1967. Because the retinal damage from plaquenil is usually irreversible if present for a more prolonged period of time, it is important to detect the disease in its early stages. Critical Warning Signs of Retinal Damage. Have you been dealing with vision problems recently that are worse than normal? If you see any of these symptoms, chances are you have retinal damage and should seek us out for assistance. Aug 14, 2017 Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Retinal damage may not improve even after Plaquenil is discontinued. Dilated eye exams should be done every six months to check for retinal problems.