Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Take plaquenil morning or night Plaquenil rash skin Hydroxychloroquine seizures Hydroxychloroquine usmle mechanism of action Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine grade c pregnancy Hydroxychloroquine Tablets - FDA prescribing information., Hydroxychloroquine MotherToBaby Plaquenil law suitsCellulitis of leg and plaquenilPlaquenil and rheumatoid arthritisPlaquenil and amoxicillin Plaquenil hydroxychloroquine is a good choice for people who have difficulty tolerating newer biologic medications. A generic form of Plaquenil hydroxychloroquine is available. chloroquine is generally safe to use during pregnancy and for children. Compare Plaquenil vs Chloroquine -. Hydroxychloroquine - Wikipedia. Safety of hydroxychloroquine in pregnant patients with.. Hydroxychloroquine -- Teratogenic Agent There is evidence to indicate that exposure to Hydroxychloroquine an antimalarial drug during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 In one study, mean peak plasma hydroxychloroquine concentrations following a single dose of 400mg in healthy subjects ranged from 53-208 ng/ml with a mean of 105ng/ml. The mean time to peak plasma concentration was 1.83 hours. The mean plasma elimination half-life varied, depending on the post administration period.