It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and lupus anticoagulant Bupropion and plaquenil Hydroxychloroquine and anxiety Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells but potentially serious eye toxicity can occur. It is unusual for plaquenil to cause muscle weakness, although it has been reported. I do not know what other medications your taking, which might have similar side effects. It is much more common to cause fatigue and ataxia, which might be mistaken for muscle weakness, but I will assume that your experiencing muscle weakness. Muscle biopsy leads to a final diagnosis in most people with myositis. There are many causes of muscle weakness and pain more common than myositis, and testing for myositis is not a. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. What type muscle weakness with plaquenil Muscle Weakness in thighs DailyStrength, Possible side effects of Plaquenil - Neurology - MedHelp Chloroquine costWill plaquenil help with fatigueHydroxychloroquine skin rash treatmentChloroquine ferroquine and ruthenoquine structure My PCP told me that it's rare to have weakness with plaquenil but more common with flexeril. I don't know if that's what's causing your muscle weakness and other symptoms but my PCP, rheumy and neurologist all have taken mine seriously, and it's not as bad as you're describing. So hopefully yours will listen this time. Plaquenil and muscle weakness - Sjogren's World. Myositis Symptoms and Causes - WebMD. Common and Rare Side Effects for Plaquenil Oral. Other causes of muscle weakness/pain. Several drugs can cause toxicity to muscle including statin drugs, hydroxychloroquine Plaquenil, colchicine, and steroids. Infections such as influenza, coxsackievirus, and Lyme disease can also cause muscle aches and weakness. This is a new question concerning an old post. Plaquenil and muscle pain. I thought that maybe my question had been answered when I read that Plaquenil was responsible for your muscle pain but, as I read on I realize it was not. I TOO have severe muscle pain and cramping in my legs. Only when trying to sleep. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work.