In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Difference between plaquenil and methotrexate Plaquenil pmr All since then I've been tested and diagnosed. Today my rheumy decided to go ahead and prescribe plaquenil. My main issues are joint, muscle and tendon pain/inflammation,As well as fatigue. Besides my possible heart and lung involvement My doc said plaquenil will help with the pain and inflammation. Will it help with the fatigue? Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hi Vanessa, My son was put on Plaquenil 9 months after being diagnosised with sine scleroderma. At the time, he had esophageal dysmotility 2/3rds of his esophagus, positive ANA, + Anti-RNA Polymerase 1/111, severe fatigue, and tightening of the chest cavity chondro. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Does plaquenil help fatigue Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Plaquenil Can you breastfeed while on plaquenilPlaquenil somnolence Is extreme fatigue a side effect of Plaquenil. Its suppose to help with fatigue and joint pain, and has slight blood thinning properties. May be worth looking at. Is extreme fatigue a side effect of Plaquenil - NRAS. Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums. Immune & Autoimmune - Lupus want to know good stuff about plaquenil. Nov 16, 2018 During my last visit, I told him I was struggling with fatigue, so he prescribed Plaquenil hydroxychloroquine. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. Plaquenil and Fatigue - from FDA reports Summary Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain.