Woman in grey hydroxychloroquine-induced hyperpigmentation

Discussion in 'Chloroquine 150 Mg' started by profimarket, 17-Mar-2020.

  1. y_wiktor New Member

    Woman in grey hydroxychloroquine-induced hyperpigmentation


    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

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    Hydroxychloroquine-related skin discoloration. Woman in grey Hydroxychloroquine-induced hyperpigmentation. clinical features and risk factors of hydroxychloroquine-induced pigmentation. Background/Purpose To describe the clinical features and outcome of hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus SLE. Method This was a retrospective, monocentric SLE clinic, Pitié-Salpêtrière, Paris study of SLE patients with pigmented lesions considered to be related to hydroxychloroquine HCQ. Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Woman in grey hydroxychloroquine-induced hyperpigmentation

    Painless, bruise-like hyperpigmentation on a woman with lupus., Talk Hydroxychloroquine-Induced Hyperpigmentation in.

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  3. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granu-loma annulare GA and started on hydroxychlo-roquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation

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    A differential diagnosis with hyperpigmentation caused by endocrine and metabolic disorders, the most closely-related disorders to drug-induced hyperpigmentation, and with hyperpigmentation of idiopathic origin, should be conducted. Drug-induced hyperpigmentation is a relatively frequent reason for consultation, especially in polypharmacy patients. Description The authors illustrate the case of a woman in her 80s with history of systemic lupus erythematosus and Sjögren syndrome. She had lost medical follow-up with her rheumatologist in the last 3 years due to progressive functional and cognitive impairment but she was still taking prednisolone 5 mg per day and hydroxychloroquine 400 mg per day for, at least, the past 11 years. A 48-year-old man with a long-standing history of systemic lupus erythematosus presented with a three-month history of mottled blue-grey hyperpigmentation on his face and on areas of previous bruising on his arms and legs Figure 11. There was no involvement of the mucous membrane or nails. His

     
  4. leo39 Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Oral Uses, Side Effects, Interactions, Pictures. Mengenal Avigan dan Chloroquine, Obat yang Dipesan Jokowi. Chloroquine phosphate C18H32ClN3O8P2 - PubChem
     
  5. 2clean Well-Known Member

    Pin it" data-description="" data-media="https://naturalon.com/wp-content/uploads/2014/04/turmeric-root.jpg" data-url="https://naturalon.com/12-of-the-best-anti-fungal-herbs-on-the-planet/" class="share-pinterest sharrre" It’s been estimated that more than a billion people have some type of fungal infection. Drugs & Medications - WebMD Chloroquine Oral Uses, Side Effects, Interactions, Pictures, Warnings. Medication Interactions That Can Cause the Pill to Fail
     
  6. kimberlit User

    Ask the Expert Plaquenil and Sjögren’s May 23, 2016 How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications.

    Plaquenil pregnancy risk of infection - What You Need to Know
     
  7. posterkun Guest

    Effects of chronic exposure of hydroxychloroquine/chloroquine. On the other hand, the risk of metastasis was significantly lower during the time of exposure. Also, hydroxychloroquine and chloroquine significantly decreased the risk of death, both in the overall population and in those diagnosed with incident cancer during follow-up.

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