Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine metallic taste Chloroquine gram negative or positive Does plaquenil suppress your immune system Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Reactions to plaquenil Plaquenil Side Effects on Your Eyes and Vision, Plaquenil Side Effects Common, Severe, Long Term - Plaquenil side effects kidneyPlaquenil prototypePlaquenil and lupus flares Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil Uses, Dosage & Side Effects -. Allergic reaction to plaquenil DailyStrength. Protecting your eyesight when taking Plaquenil Lupus.. Hallucinations, seizures, and hearing loss are among the serious side effects of Plaquenil. This eMedTV Web page provides a more in-depth list of potentially dangerous reactions and explains when to report such problems to your doctor. She said that plaquenil was the least likely to cause liver issues. I did read that there is a small possibility that was maybe the brand. Has anyone had a reaction to the generic, but then did ok with the name brand Plaquenil? Or anyone else that had such a severe reaction to Hydroxycloroquine but did well with another med entirely? This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox?