In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Plaquenil price increase 2016 Plaquenil 100 mg Plaquenil does relieve much of the fatigue. As for the joint pain, still a problem. As for the joint pain, still a problem. Yes, depression is an issue, still is. Is extreme fatigue a side effect of Plaquenil - NRAS. Is extreme fatigue a side effect of Plaquenil. I've been on Plaquenil now for three months and its starting to help with the pain although I have diarrhoea every day but it's manageable. But I'm really struggling with fatigue now - worse than its ever been. Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. While there is good clinical evidence demonstrating. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Does plaquenil help with fatigue Does plaquenil help with fatigue. DailyStrength, Is extreme fatigue a side effect of Plaquenil - NRAS Buy plaquenil 200mgPlaquenil thrombocytopeniaRa and plaquenil Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Is lethargy and tiredness a side effect of hydroxychloroquine?. Ask the Expert Plaquenil and Sjögren’s. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Exercise and iron infusions have done the brunt of the work, but it’s plain to see that even in the short term, Plaquenil has given me a much-needed boost. Has anyone's doctor suggested Plaquenil for chronic fatigue syndrome? My rheumy has a couple of times. He says it could help with energy level because it is an immune enhancer. My mother took it for rheumatoid arthritis years ago and thinks it's worth a shot. My only concern is the. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites.