It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. When is it best to take plaquenil Can hydroxychloroquine cause insomnia Can hydroxychloroquine cause weight loss In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. If you become pregnant while taking this drug. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Hydroxychloroquine sulfate and pregnancy HYDROXYCHLOROQUINE SULFATE Warnings Pregnancy & Lactation., Hydroxychloroquine Use During Pregnancy Effect of chloroquine on liver enzymesChloroquine endosomeDoea plaquenil affect the immune systemHydroxychloroquine 200 mg overdose Hydroxychloroquine sulfate salt 200 mg is equivalent to hydroxychloroquine base 155 mg. Dermatomyositis, cutaneous disease off-label use. Pregnancy Considerations. Hydroxychloroquine can be detected in the cord blood at delivery in concentrations similar to those in the maternal serum Costedoat-Chalumeau 2002. Hydroxychloroquine Professional Patient Advice -. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil and Pregnancy - Antibiotics Home Page. Hydroxychloroquine is usually considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using hydroxychloroquine during pregnancy see Plaquenil and Pregnancy for more information. HYDROXYCHLOROQUINE. DESCRIPTION Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolyl aminopentyl ethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine Hydroxychloroquine crosses the placenta, but is considered safe to use during pregnancy. 299 Hydroxychloroquine does appear in breast milk, but the amount ingested per day by a breastfeeding infant would be very low. 300 It seems reasonable for a mother taking hydroxychloroquine to breastfeed if she had taken hydroxychloroquine during pregnancy.