In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Is there a difference between plaquenil and generic Plaquenil eyesight Can you take aleve with plaquenil Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation. Arch Dermatol 1985;164-1166 Ten white men 19-21 years of age, belonging to the South African defence forces showed dark pigmentation of gums; 4 subjects had also a dark pigmentation of the whole body including the nail bases, nipples and scars. Chloroquine-induced, vitiligo-like depigmentation. patients with vitiligo who visited the Netherlands Institute for Pigment disorders from January 2003 to December 2007. Chloroquine. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)A, Bluish-green pigmentation on the legs in a patient with systemic lupus erythematosus without lupus lesions at the time of the skin biopsy. Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Chloroquine-induced pigmentation Hydroxychloroquine-Induced Pigmentation in Patients With., Chloroquine-induced pigmentation case reports. Aralen canadaHydroxychloroquine cancer stem cells Chloroquine-induced itching is very common among black Africans 70%, but much less common in other races. It increases with age, and is so severe as to stop compliance with drug therapy. It is increased during malaria fever; its severity is correlated to the malaria parasite load in blood. Chloroquine - Wikipedia. Chloroquine-induced, vitiligo-like depigmentation Request PDF. Chloroquine-Induced Hair Hypopigmentation NEJM. Images in clinical medicine The new england journal of medicine 372 n engl j med 363;4 july 22, 2010 A 16-year-old, blonde-haired patient was evaluated for a new band of lighter-colored. There was no pigmentation at other body sites. Biopsy from the plaque showed necrobiotic collagen with intradermal mucin and perivascular lymphohistiocytic infiltrate accompanied by brown coarse pigment in the dermis figure 1C,D. The pigment was negative on Perl’s stain. This was a unique pattern of HCQ pigmentation seen in our patient. Pigmentation to manifestations of systemic illnesses e.g. Addison’s disease and malignant neoplasms e.g. melanoma and Kaposi’s sarcoma. Therefore, an understanding of the causes of mucosal pigmentation and appropriate evaluation of the patient are essential. Oral pigmentation may be exogenous or endogenous in origin.