Hydroxychloroquine in lupus pregnancy.

Discussion in 'Canadian Pharcharmy' started by Aston, 02-Mar-2020.

  1. sergey74 Well-Known Member

    Hydroxychloroquine in lupus pregnancy.


    This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus.

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    Hydroxychloroquine Plaquenil and prednisone are considered safe during pregnancy. Methotrexate and cyclophosphamide Cytoxan should not be used in pregnancy and should be discontinued for at least a month prior to getting pregnant. Ask your doctor to help you weigh the benefits and risks all your medications. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. Objectives. Systemic lupus erythematosus SLE is a chronic autoimmune disease that primarily affects women of childbearing age. While the impact of hydroxychloroquine HCQ on SLE activity and neonatal lupus occurrence has been evaluated in several studies, its role on prematurity and intrauterine growth restriction IUGR remains uncertain.

    For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®.

    Hydroxychloroquine in lupus pregnancy.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine in lupus pregnancy - Clowse - 2006.

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  5. Clowse et al. found that women who stopped taking HCQ had increased lupus activity and increased lupus flares during pregnancy. High activity lupus was defined as a physician's estimate of activity PEA greater than 2 occurred in twice as many pregnancies in which HCQ treatment was stopped as in those in which HCQ was continued.

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    OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine HCQ. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye.

     
  6. alexandr_aa7a New Member

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil Hydroxychloroquine Sulfate Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Despite Plaquenil dosing recommendations, retinal toxicity.
     
  7. Vandervild Moderator

    Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). What is the correct way to discontinue use of plaquenil? Hydroxychloroquine Plaquenil MPKB Hydroxychloroquine hi-drox-ee-CLOR-oh-kwin
     
  8. nayiki XenForo Moderator

    Medicinal Chemistry of Antimalarial Drugs The following article looks at the medicinal chemistry of antimalarial drugs. It will look at – in detail – quinine and quinine-related drugs. In a previous article, we briefly described malaria and artemisinin as a lead compound for new antimalarials. We now turn our attention to the other antimalarial drugs.

    Malaria - SlideShare
     
  9. fianit New Member

    Combination hydroxychloroquine and sulfasalazine - do. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa.this combination worked for anyone? just wondered how other people got on with it.

    Compare Plaquenil vs Sulfasalazine - Comprehensive Analysis.