Retinal exam hydroxychloroquine frequency

Discussion in 'Canadian Pharcharmy Online' started by 4717, 25-Feb-2020.

  1. LeXuZZ User

    Retinal exam hydroxychloroquine frequency


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some. Because hydroxychloroquine HCQ–related retinal toxicity risk can be minimized by performing a baseline retinal examination that allows early detection of changes, multiple past clinical guidelines have recommended baseline retinal examinations for all patients initiating HCQ therapy. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Retinal exam hydroxychloroquine frequency

    Plaquenil Side Effects on Your Eyes and Vision, Baseline Retinal Examinations in Patients With Systemic Lupus.

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  4. In a demographic study, the rate of hydroxychloroquine-induced retinal toxicity was thought to be near 7.5%.

    • New Guidelines for Hydroxychloroquine Visual Screening.
    • Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses.
    • My Take on New Ocular Screening Guidelines for Plaquenil..

    Or higher - up to 400 mg Plaquenil daily; 5’ 1/2” to 5’ 6 1/2” - up to 300 mg Plaquenil daily; 5’ or shorter - up to 200 mg Plaquenil daily; Women with lupus who are AT OR BELOW their ideal body weight should go by these dosing rules 135 lbs. or more, any height - up to 400 mg Plaquenil daily Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. The AAO recommend that screening visits should include subjective tests and at least one objective test, where such tests are available. Subjective tests include detailed ophthalmologic examination visual acuity, corneal examination, retinal exam through a dilated pupil and an automated visual field test Humphrey 10-2 test.

     
  5. dwd_pavel XenForo Moderator

    Rheumatoid arthritis is an autoimmune disease that is treated with a variety of medications, including non-steroidal anti-inflammatory drugs, or NSAIDs, and disease modifying anti-rheumatic drugs, or DMARDs. Hydroxychloroquine - LiverTox - NCBI Bookshelf Plaquenil Uses, Dosage & Side Effects - Autoimmune hepatitis - Diagnosis and treatment - Mayo Clinic
     
  6. wolkodlak-shadow Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. What next if plaquenil doesn't work? - Scalp Pain, sensitivity, burning, and Hair Loss Women's. Plaquenil - FDA prescribing information, side effects and uses
     
  7. mvo User

    Hydroxychloroquine Uses, Dosage & Side Effects - Mar 17, 2019 Take hydroxychloroquine exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Hydroxychloroquine is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule.

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  8. Zikdelk Moderator

    PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION Results following a single dose of a 200 mg tablet versus i.v. infusion 155 mg, demonstrated a half-life of about 40 days and a large volume of distribution. Peak blood concentrations of metabolites were observed at the same time as peak levels of hydroxychloroquine. The mean fraction of the dose absorbed was 0.74.

    Plaquenil Brand vs Generic - Sjogren's World