Plaquenil (hydroxychloroquine) is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Prevents and treats malaria, and also treats a type of bowel infection. Plaquenil visual field testing Plaquenil use icd 10 code Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine is a member of the drug class 4-aminoquinoline. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Structure, properties, spectra, suppliers and links for Chloroquine Phosphate, 1446-17-9. Log Octanol-Water Partition Coef (SRC): Log Kow (KOWWIN v1.67 estimate) = 4.50 Log Kow (Exper. Sorption to aerosols (25 Dec C)[AEROWIN v1.00]: Vapor pressure (liquid/subcooled): 0.000568 Pa (4.26E-006 mm Hg) Log Koa (Koawin est ): 14.989 Kp (particle/gas partition coef. Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people. 2d chemical structure of chloroquine Chloroquine Ligand page IUPHAR/BPS Guide to PHARMACOLOGY, Chloroquine Sigma-Aldrich Plaquenil side effects gasPlaquenil causing low wbc countChloroquine lichen planus The combination of chloroquine with zinc enhanced chloroquine's cytotoxicity and induced apoptosis in A2780 cells. Thus chloroquine is a zinc ionophore, a property that may contribute to chloroquine's anticancer activity. Chloroquine Is a Zinc Ionophore - PubMed Central PMC. Chloroquine Phosphate C18H29ClN3O4P ChemSpider. Chloroquine hydrochloride - DrugBank. Chloroquine sulfate is an alkaloid sulfate salt. It contains a chloroquine. The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. To resolve this problem, over the years, I compiled chemical names and identifiers into a personal database, cross referencing regulatory and health safety information when possible. Colleagues and friends eventually started suggesting that I make my data available on this website so that others could benefit from my efforts -- which I finally. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion.