Carole, Just curious, did you try the generic (hydroquix...)or brand name Plaquenil? When I started Plaquenil, my GI system was in an uproar. I couldn't tolerate the generic, but the brand name has a coating for the stomach. Plaquenil pregnancy category arthritis Can i take ibuprofen and plaquenil Hydroxychloroquine myositis Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Is there a drug that I can take to replace plaquenil? Asked by tanner01 Updated 5 April 2018 Topics plaquenil, rheumatoid arthritis, methotrexate. I take methotrexate also but the plaquenil messed with my vision and I had to quit taking it. I been treated for ra for 19 yrs. And I'm beginning to see more changes in my feet and hands. In some cases, they may not be available in every strength or form as the brand-name drug. Wallace's book and found the stats, plus my rheumie telling me much the same, that many people with lupus (something like 40% or more) "present" with GI problems. Meaning long enough to start to sort out whether your problems were mainly from the disease or from the med? Substitute for hydroxychloroquine Recommendations on Screening for Chloroquine and., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Is chloroquine available over the counterChloroquine hallucinations robert baleDoes hydroxychloroquine lower immune system Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar.. Is there a drug that I can take to replace plaquenil?. Alternatives to plaquenil Anti-Inflammatories.. I have taken Plaquinel/hydroxychloroquine at a low dose as maintenance for my SLE for over 20 years. No side effects. No problems. Until I went on Medicare and they don't want to pay for it. They want me to try cheaper alternatives before they will pay for hydroxychloroquine. I can take it but I would have to pay a high price for it. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.