Information also provided for 3,600 nuclides and 4,400 nuclide decay modes. Editor's note: Some chemicals in this database contain more information than others due to the original reason this information was collected and how the compilation was accomplished. Chloroquine aralen Plaquenil mixed with alcohol Hydroxychloroquine ankylosing spondylitis Estradiol plaquenil combination The novel finding of the present study is that chloroquine is a zinc ionophore, which contributes to our understanding of chloroquine's biological activity in human cancer cells. While chloroquine has been studied in biomedical research 12, 13 and used for the treatment of malaria 1 and other human diseases 25, 26, this activity of the compound has not been previously reported. We have detected that you are are on a small device such as a mobile phone. We recommend you use a larger device to draw your structure. Still want to try? Try rotating the device so that it is in a landscape position. The aminoalkyl side chain in chloroquine helps in the accumulation of the drug inside the food vacuole and assists in the complexation of the quinoline nucleus with the porphyrin system. Modification of this side chain either by varying its length or attaching new chemical groups can circumvent chloroquine resistance. To resolve this problem, over the years, I compiled chemical names and identifiers into a personal database, cross referencing regulatory and health safety information when possible. While working with material safety data sheets (MSDS), I found that manufacturers sometimes used obscure names for constituent chemicals and I didn't always have a good idea of what I was dealing with. Chemical structure of chloroquine Hydroxychloroquine C18H26ClN3O - PubChem, Chemical Structure Search - ChemSpider Plaquenil alcohol liver Chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. ADVERTISEMENT Compare Plaquenil vs Chloroquine -. Chloroquine - an overview ScienceDirect Topics. S-Chloroquine C18H26ClN3 - PubChem. Chloroquine is a 4-aminoquinoline and used primarily as an antimalarial drug. The approved drug is a racemic mixture and we show the chemical structure without stereochemistry to represent the mixture. Search results for Chloroquine at Sigma-Aldrich. Summary This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Chemical Class An aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoe biasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.