Its cause is not known, and most episodes of granuloma annulare clear up after a few years, with or without treatment. Although granuloma annulare can occur in people of any race and at any age, it is most commonly seen in children and young adults. Does plaquenil effect healing after bone surgery Fatcs on chloroquine Plaquenil reviews for ra Is hydroxychloroquine sulfate an immunosuppressive drug Granuloma annulare GA is a benign inflammatory disease associated with many conditions such as malignancy, trauma, thyroid disease, diabetes mellitus, and HIV infection. Common clinical subtypes include localized GA, generalized GA, subcutaneous GA, perforating GA, and patch GA. While there is limited evidence for their use in this indication, antimalarial agents e.g. hydroxychloroquine or chloroquine are the most widely supported and most often used first-line drugs. Grewal SK, Rubin C, Rosenbach M. Antimalarial therapy for granuloma annulare results of a retrospective analysis. Dermatology. 2005;2112167-8. Treatment of generalized granuloma annulare with hydroxychloroquine. Cannistraci C, Lesnoni La Parola I, Falchi M, Picardo M. The lesions of granuloma annulare are usually found in the same areas on both sides of the body (symmetrically). Females are slightly more likely than males to develop granuloma annulare. Chloroquin andgranuloma annulare List of Granuloma Annulare Medications 7 Compared -, Granuloma annulare - Treatment algorithm BMJ Best Practice Interactions between flecainide and hydroxychloroquineSpectral-domain optical coherence tomography in hydroxychloroquine retinopathy Chloroquine and its congeners can cause two typical adverse effects in the eyes keratopathy and retinopathy. Both of these effects are associated with the administration of the drugs over long periods of time. Chloroquine-induced keratopathy is limited to the corneal epithelium, where high concentrations of the drug are usually used. Chloroquine analogues in drug discovery new directions of uses.. Treatment of generalized granuloma annulare with.. Granuloma Annulare - Pictures, Causes, Contagious, Symptoms, Treatment.. What is granuloma annulare? Granuloma annulare is a long-term chronic skin disease consisting of a rash with reddish bumps arranged in a circle or ring. Granuloma annulare is a common and benign skin condition that produces ring-shaped lesions, generally on the hands and feet. Its exact causes are unknown. Although there is no known cure and it generally self-resolves, dermatologists may recommend various treatments to alleviate the symptoms. Granuloma Annulare Granuloma annulare is a benign dermatosis. The etiology of granuloma annulare is unclear and the delayed type of hypersensitive reaction to unknown antigen is supposed. We distinguish localized, generalized, perforating, subcutaneous and patch form of granuloma annulare.