Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine sulphate tablets zy-q 200 Plaquenil generic name In regards to malaria what is chloroquine resistance Hydroxychloroquine with or without food Toxicity causes a parafoveal or extramacular loss of photoreceptors and the retinal pigment epithelium layer RPE. End stage maculopathy causes a bull’s eye pattern of RPE loss as well as possible cystoid macular edema, loss of central and peripheral vision as well as night vision. Blurred vision, light sensitivity, seeing halos around lights, pale skin, easy bruising or; bleeding, confusion, unusual thoughts or behavior, or; seizures convulsions. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. In advanced cases of retinal toxicity from Plaquenil, there can be loss of visual acuity, peripheral vision, and night vision. Most documented cases of Plaquenil retinal toxicity are related to large cumulative lifetime doses over a period of many years. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil retinal toxicity night vision Conditions Plaquenil-related Eye Problems Eugene Eye Care, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Chloroquine resistance wikiAao plaquenil guidelines When vision is impacted it can include paracentral scotoma early decreased color vision early reduced acuity late reduced peripheral vision late reduced night vision late Signs. The classic sign of hydroxychloroquine retinopathy is bilateral “bull’s-eye” appearance of the macula due to disruption of the retinal pigmented epithelium. Plaquenil Toxicity -. Medications that can Affect the Eye or Visual System. PowerPoint. Update on Plaquenil Testing. End stage hydroxychloroquine toxicity leads to widespread RPE and retinal atrophy with a loss of central vision, peripheral vision, and night vision. Recent studies have shown that patients of Asian descent develop initial damage in a more peripheral extramacular distribution near the arcades, most frequently in the inferotemporal region with. Retinal!toxicity.and!it!has!largely!replaced!chloroquine!as!a!treatment!ofinflammatory!disease. Unfortunately.the!retinal!damage!from!these!medications. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.