It is a rare but life-threatening condition that develops when narrowed vessels, which are responsible for transporting the blood from the heart to the lungs, force the heart to work harder to pump blood. In that case, the heart can become large and weak, resulting in right heart failure. Plaquenil poisoning Plaquenil and extreme fatigue How long does it take for plaquenil to start working High blood pressure is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. Pulmonary Hypertension and Lupus Diagnosis and Prevalence Pulmonary hypertension and lupus is more common among Caucasian and female patients younger than patients typically with PH. Early diagnosis if important because the effects can PH can worsen the symptoms of lupus. Hypertension High Blood Pressure Fifty percent of people with lupus experience hypertension high blood pressure, which is defined as a blood pressure of greater than 140/90 mmHg. In addition, many more lupus patients have blood pressures greater than the normal 120/80 mmHg limit. There are cases in which the causes are not determined, known as idiopathic pulmonary hypertension. Identifying the reasons for the development of PH is one of the first and most important steps to properly treating the condition. Plaquenil and hypertension Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Pulmonary Hypertension and Lupus Switching from methotrexate to plaquenil Feb 19, 2020 Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. How Does Lupus Affect the Cardiovascular System Johns.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine HCQ, a common anti-rheumatic medication, can be cardiotoxic and cause systolic or diastolic heart failure HF. A 65 year old man presented with acute decompensated HF. He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years.