Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil positive reviews Can plaquenil cause weight gain Plaquenil and psychosis Plaquenil similar Dec 04, 2014 This baseline evaluation entails a dilated fundus examination, 10-2 white pattern visual field test subjective, and at least one of the following objective tests Spectral-domain optical coherence tomography SD-OCT, fundus autofluorescence FAF, or multifocal electroretinogram mfERG. FUNDUS AUTO FLUORESCENCE The fundus auto fluorescence confirms Plaquenil toxicity, worse in the left eye than the right eye with an area in the right eye of hyperfluorescence in the macula and the left eye there is an area of hypofluorescence in the macula. Fundus Autofluorescence FAF. Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Fundus autofluorescence plaquenil How to Succeed in Plaquenil Screenings, Plaquenil Toxicity - Mild - Partial Bull's Eye Maculopathy. Plaquenil causing lymphomaPlaquenil 200 mg brcl Jan 01, 2011 Fundus autofluorescence is a noninvasive, rapid and potentially useful imaging modality that continues to evolve. FAF reflects metabolic changes in the RPE and thus provides an assay of retinal and RPE function. Fundus Autofluoresence Imaging Principles and Applications. Early Plaquenil Toxicity Detected without Bull’s Eye.. Fundus Autofluorescence and Spectral Domain Optical Coherence.. Fundus autofluorescence FAF is a non-invasive imaging technique that detects fluorophores, naturally occurring molecules that absorb and emit light of specified wavelengths 1. To produce autofluorescence, a fluorophore absorbs a photon of the excitation wavelength, which elevates an electron to an excited, high energy state. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily Ivocal signs of chloroquine maculopathy bilateral peri-central scotoma in the visual fields, structural alterations of the macula in the optical coherence tomography but normal or atypical findings as to fundus autofluorescence imaging. Results In all patients, optical coherence tomography showed perifoveal thinning and subtle alterations of the outer retinal layers. In one patient, the.