Also had to have an occupational health meeting today for my job as not worked for 6 months now and hoping they make me redundant as i can't work as a waitress with ra due to pain and flares in my opinion. (others may do) and i then can get benefits till i find a job i can do with the ra(i am not doing this just for benefits, i hope people understand that) I have now been on Plaq for just over three years and MTX for just under three years. Cheap aralen malaria Side effects with plaquenil Vision test for plaquenil Plaquenil and lung cancer Methotrexate In treating lupus, prednisone and the anti-malarial drugs such as Plaquenil remain the cornerstone of treatment because of their effectiveness and safety. Because of some of the side effects, some people do not respond well to prednisone and Plaquenil. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. The first two weeks weren't bad, as Plaquenil has a high half-life and there was still some Plaquenil in my body. After that, my Lupus got progressively worse until I gave up and re-started the Plaquenil after 6 weeks of being off it. My Rheumy suggested MTX and told me it would be months before we knew for sure it would work. The combination works well for me-though I also take a NSAID. I started feeling better about a month after starting plaq-I was also on prednisone at the time-but couldn't get all the way well. Methotrexate and plaquenil for lupus Methotrexate MyLupusTeam, Plaquenil hydroxychloroquine sulfate dose, indications. Incidence of adverse affects to chloroquineChloroquine malariaPlaquenil freshness disposal Lupus and Plaquenil research. While Plaquenil was not created with the explicit purpose of helping people minimize the disease activity of lupus, a number of clinical trials have been conducted to examine the clinical impact of the medication. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Taking methotrexate with hydroxychloroquine has. He was treated instead with low-dose oral methotrexate. Comment. Ultraviolet light is contra-indicated for patients with lupus, and prednisone is relatively contra-indicated for psoriasis. This is a case where Plaquenil likely triggered new-onset psoriasis in a patient who was genetically susceptible.