But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Sle hydroxychloroquine dose Does plaquenil cause heartburn Can tramadol and hydroxychloroquine be taken together Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria C-Quinicrin is an alternative to Plaquenil that worked REALLY well for me. The last I heard it was no longer in the US, so I have been been without it and feel miserable. Has anyone found a way to buy it in Canada or elsewhere. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Lupus alternatives to plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Has anyone been on C-Quinicrin? It is an alternative to. Antimalarial hydroxychloroquine Hydroxychloroquine, brand name Plaquenil, is a time-tested and often-used medication that is typically a first line of defense in the treatment of autoimmune conditions such as RA and lupus. Plaquenil Shortage Leaves RA, Lupus Patients in Pain and.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Contemporary treatment of systemic lupus erythematosus an.. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. So other meds like Imuran and CellCept mycophenolate mofetil also reduce flares, but also increases infection. I am so afraid to take plaquenil for lupus treatment! any natural cure? Does anyone has an experience with plaquenil? or some one knows a natural way to cure lupus? I am currently taking oil fish, cellfood and recovery for joint pain and multi-vitamins. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues. Dry skin. Loss of appetite. Abdominal bloating. Upset stomach. Stomach cramps. Retinal damage.