Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Plaquenil antibiotic Lysosomal inhibitor chloroquine Patients need prescription drugs like pilocarpine Salagen or cevimuline Evoxac. Yeast infections can be treated with anti-fungal medicines, and patients with reflux may use drugs to reduce stomach acid, like proton-pump inhibitors or H2 blockers. Some people with Sjögren’s syndrome may need hydroxychloroquine Plaquenil. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease. Sjogren's Syndrome Support Group. Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Does plaquenil reduce rheumatoid factor in patiences with sjogrens Hydroxychloroquine User Reviews for Sjogren's. -, Taking Plaquenil for Rheumatoid Arthritis Plaquenil ringing in earsPlaquenil poisoning Year old female diagnosed with primary sjogrens in spring of '19. Luckily was able to see my rheumatologist quickly and am currently on plaquenil 400mg every day. Sadly I started noticing excess hair shedding and I know that's a side effect of plaquenil. Plus I have fun dying my hair crazy colors which also involved bleaching. Plaquenil hair loss nioxin review Sjogrens. Weakened immune system? DailyStrength. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. About half of people with Sjogren's also have another autoimmune disease, like rheumatoid arthritis or lupus. That can sometimes make it harder for your doctor to give you a diagnosis. A B cell activation results in hypergammaglobulinemia with elevated levels of circulating immune complexes and production of autoantibodies. Among the autoantibodies seen are rheumatoid factors RF, anti-Ro/SSA and anti-La/SSB 1 – 4. RF is found in the serum and saliva of 60–80% of pSS patients 5, 6. I may be incorrect and someone please correct if I am, but I believe plaquenil is used for sjogrens and lupus primarily, but can be used in RA as well as other AI diseases It is often the "first line of defense" with sjogrens and lupus before the rheumys pull out the bigger guns like methotrexate and others.