Chloroquine in breastfeeding

Discussion in 'Aralen' started by Yakon, 27-Feb-2020.

  1. spiny-1984 Guest

    Chloroquine in breastfeeding


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Very small amounts of chloroquine are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. United Kingdom malaria treatment guidelines recommend that weekly chloroquine 500 mg be given until breastfeeding is completed and primaquine can be given.1 Breastfeeding infants should. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. This information should not take the place. Can taking chloroquine in pregnancy cause my baby to be small at birth low birth weight? Eleven studies have investigated whether chloroquine use in pregnancy may affect a baby’s birth weight. Eight of these studies showed that women taking chloroquine did not have a higher chance of having a baby with a low birth weight 2,500 g.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine in breastfeeding

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    Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. The excretion of chloroquine and the major metabolite, desethylchloroquine, in breast milk was investigated in eleven lactating mothers following a single oral dose of chloroquine 600 mg base. The maximum daily dose of the drug that the infant can receive from breastfeeding was about 0.7% of the maternal start dose of the drug in malaria. We hypothesize that the high accumulation of chloroquine in mammary cells actively replicating HIV-1 should allow the drug to inhibit HIV replication. Therefore, maternal chloroquine administration during the breastfeeding period may decrease milk viral load, and therefore lower the risk of breastfeeding-related transmission.

     
  5. antimaul XenForo Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Breakthrough Chloroquine phosphate has shown apparent. Chloroquine - Wikipedia Where To Buy Chloroquine Phosphate
     
  6. CybFreak Well-Known Member

    Some side effects may occur that usually do not need medical attention. Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy. Is extreme fatigue a side effect of Plaquenil - NRAS Is extreme fatigue a side effect of Plaquenil?
     
  7. erdao Guest

    Mylan Ramps Up U. S. Manufacturing of Hydroxychloroquine Sulfate Tablets. Mylan Ramps Up U. S. Manufacturing of Hydroxychloroquine Sulfate Tablets to Meet Potential COVID-19 Patient Needs. additional ways we may be able to assist in the massive prevention, diagnosis.

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  8. robgor Moderator

    PLAQUENIL - Indicaciones, Dosificación, Presentación, Efectos. Indicaciones de PLAQUENIL. Lupus eritematoso y artritis reumatoidea el sulfato de hidroxicloroquina se usa para el tratamiento del lupus eritematoso discoide crónico y sistémico y la artritis reumatoidea crónica y aguda, especialmente en pacientes que padeciendo estas enfermedades no responden satisfactoriamente a drogas con menores efectos secundarios.

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